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By: Jill Loeffler • Published: October 26, 2015 • Updated: February 19, 2025
Hop aboard one of these cruises from San Francisco and enjoy the ultimate vacation experience. From Pier 27 in SF, you will find trips with destinations to Alaska, Mexico, and Hawaii.
You can also enjoy a longer cruise through the Panama Canal or over to the South Pacific. In addition, you will also find some shorter cruises to the ports on the western coast of the US.
There are several cruises that leave SF each month. Many of them offer round trip service to your destination and back. However, the longer options usually end in a secondary location.
Read on to learn more about the various ocean journeys that start in SF.
Disclaimer: I receive a small commission from some of the links on this page.
This is a great section for those looking to book a cruise that leaves from San Francisco. The date listed is when it departs from San Francisco.
My calendar offers upcoming cruises for both 2025 and 2026 by month.
In this section, I organized all of the upcoming cruises for you by destination.
The most popular cruises from San Francisco take visitors through the Alaska Inside Passage. This journey offers you a chance to see the wild beauty of Alaska up close. Most have three stops in Alaska as well as one in Canada.
The highlight of these cruises is the journey through either Tracy Arms Fjord or Glacier Bay. While you don't dock on these days, you do spend a number of hours cruising around these amazing natural wonders.
San Francisco offers two wonderful cruises to the Hawaiian Islands. They both stop at four places among the islands, including Honolulu, Maui, and Hilo.
These cruises also make a short evening stop at the waterfront town of Ensenada, Mexico.
Enjoy a cruise from San Francisco to the Mexican Riviera. This lively trip offers you the chance to visit several ports of call on Mexico's western coast.
You will stop in places such as Puerto Vallarta, Mazatlán, and Cabo San Lucas.
Head south on the Pacific and through the Panama Canal. These tours stop in several locations on the way, including Mexico, Costa Rica, and Guatemala or Nicaragua.
For one full day, you get the chance to enjoy the beauty of the Panama Canal. You will then continue your journey and stop in locations such as Columbia, the Bahamas, or Aruba.
Most of these cruises end their adventure in Fort Lauderdale, Florida.
Are you planning a visit to SF during your cruise? If so, you will find a wide variety of shore excursions for your stop. You can also check out some of my self-guided tours that will help you quickly and easily get to as many different attractions in one day as possible.
Here are five fun options.
The best place to start the booking process is by checking out the deals being offered. You will find some deals directly on the cruise companies' websites as well as through third-party booking agencies.
Here are links to a few of the sites where you can discover the best deals for cruises from San Francisco (and beyond!):
Do you need to store your luggage for a few hours or all day in SF? Here are a few places that allow you to store your luggage.
Stasher Luggage Storage: The best way to find a spot for your luggage is to head over to the Stasher Luggage Storage website. Here you can find locations for storage and book a spot ahead of time. They charge just $6 per day, which includes insurance up to $1000. Visit their site for details.
SFO: You can also store your luggage at the Airport Travel Agency in the International Terminal at SFO. They charge by the day. If you only leave it for a few hours, they will still charge the daily rate. They do scan all luggage that is set to be stored before they accept it. They are open daily from 7 am to 11 pm and you will find them near the Departures/Ticketing area.
Local Hotels: Many of the local hotels will allow you to store your luggage with their concierge. Your best bet is to call them ahead of time, tell them your story, and they will tell you if they allow it or not.
I would contact the larger chains such as Marriott or Hyatt as you have a better chance of them offering this service than others. These hotels will often take your name and ask when you will be arriving.
Most of the time, you do not need to be a hotel guest to receive this service. However, please be courteous and leave them a nice tip for this service.
With the opening of Pier 27 a few years ago, San Francisco now offers several cruise options from a number of lines. You'll find the largest variety of cruise destinations operated by Princess Cruises.
Cunard Line: Cunard offers luxury cruises all around the world. It's perfect for those who love to dress up each day for their adventures, dining, and other activities. The great thing about this cruise line is that you are allowed to start and stop your cruise at many destinations throughout the world. This offers you the chance to make your cruise as short or as long as you'd like.
There are several routes that leave from San Francisco. Most head toward Hawaii first, then on to New Zealand and Australia. Others continue up through Southeast Asia, along the eastern African coast down to South Africa, back up the western side of Africa, on to Spain, and then finish in England or even New York.
All tours are on the Queen Elizabeth, Queen Anne, or Queen Mary 2, which offer room for up to 2,000 passengers.
Norwegian Cruise Line: Norwegian offers a couple of cruises that originate in San Francisco. The most popular is the one to Miami through the Panama Canal.
Princess Cruises: Princess Cruises offers the largest number of cruises leaving from SF. They offer 8 cruises with destinations around California, Hawaii, Alaska, Mexico, and the Panama Canal.
Regent Seven Seas Cruises: Regency Seven Seas is the final company that originates cruises from San Francisco. They also offer an 18-day cruise to Miami through the Panama Canal.
The best way to get to Pier 27 is by public transit. As you can see in the picture below, you will find a streetcar stop right across the street from the pier.
You can take the historic F streetcar along the Embarcadero going south from Fisherman's Wharf or north from Market Street.
You can get off at either the Sansome or Greenwich stop. You can also ask the driver to alert you when you arrive at the stop for the cruise port.
If you plan to drive, there are a few parking options nearby. I do have to warn you that parking is VERY expensive (up to $30 or more a day) in San Francisco and I only recommend this if you do not have any other options.
Here are a few parking garage options within walking distance:
Before you leave your car, make sure to review their regulations. These change frequently, as well as the pricing, so confirm that they offer 24-hour parking and what the daily rate is before you leave your car.
Most people taking cruises from San Francisco enjoy staying a night or two before or after their visit. There are quite a few fun activities and attractions here, so, if you can, I recommend extending your trip dates a little to explore SF.
Also, it's best to stay in Fisherman's Wharf. It's an easy walk, cab ride, or streetcar ride to Pier 27. Here are a few of the best options.
Hi, I'm Jill!
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